Friday, May 10, 2019

Does CBD Impact Progesterone and Estrogen?

Progesterone along with estrogen are known as female sex hormones, which play a big role in the reproductive system and organs, improving the well-being of the body for women. CBD can modulate the way that these are expressed, but right now, this is still at the early stages. 

How these hormones Work 

The hormones are used as ways to receive messages that are impacted by the endocrine glands, and this triggers the changes.  You have a master gland, which is the pituitary gland.  Men along with women actually have the same hormones, just expressed differently. Progesterone along with estrogen are what’s seen in women, testosterone in men. But men can produce the same, but it’s at lower levels. 



For those who don’t know, progesterone is basically the building block which makes the sex hormones that’s there. the ovaries and testes both create these, but they play a role in the regulating of menstrual cycles, and it can impact how sperm production happens in guys. 

Progesterone also helps with a lo of functions, such as: 

  • Improving blood sugar 

  • Controlling and increasing bone mass 

  • Controlling brain activity 

  • Converting fat stores into energy 

  • Controlling the production of thyroid hormones 

  • Improves libido 

  • Improves mood 

  • Supports sleep 

Estrogen is pretty much what helps with sex drive, erectile function, and sperm production in men.  For women, this s what helps with the egg follicle growth, the thickness of your uterus, uterine health, forming breast tissue.  This is something that is also changed based on the different stages people are in. 



It also helps increase the following: 

  • Bone density 

  • Changing physical features when puberty hits 

  • Maintaining emotions and mood 

  • Skin that’s healthy 

  • Improving your cognitive skills 

  • Boosting muscle mass 

  • Metabolism 

The Science of CBD and these hormones 

Right now, the effects of CBD on these are still in the early stages. Right now, most of the research that’s there looks at the whole plant, on these hormones 

The interaction of both of these offer an increase in the production of hormones, followed by the entourage effect, so it can help with improving this in a person. 

But they can also modulate the way the hormones work within the ECS, and it can help with increasing the hormonal functions. 



In a study done in 1980, it was found that the high levels of CBD didn’t change our estrogen levels, but it wsa found that CBD actually did suppress the production, since it can inhibit aromatase production.  This is important for the production of this. It can also deregulate the decidualization, which is something that plays a part in pregnancies. It wsa found that it can lead to problems with fertility, but it requires more research before the agree to conclude that.

The findings of this on progesterone were done mostly on rat studies. It wsa found hat it can actually inhibit progesterone expression within the rats. Some do theorize that this might’ve bene created due to the metabolic interactions between the enzyme and the cannabinoid which creates this. This is something that it  could possibly be an issue, but we need more studies. 

Right now, ther is nothing that says CBD can ruin pregnancies, or impact the production of this, but as you use it, know that this is a study without too much behind it, due to the fact that most of the studies are done with the whole plant, rather tan just an isolate, so it’s important to look at this, and also note that it may create hormone imbalance.